{"id":45,"date":"2009-07-10T15:40:09","date_gmt":"2009-07-10T07:40:09","guid":{"rendered":"http:\/\/farmasi.dikti.net\/?p=45"},"modified":"2009-07-10T15:40:09","modified_gmt":"2009-07-10T07:40:09","slug":"suppositoria-jangan-dimakan","status":"publish","type":"post","link":"https:\/\/apoteker.net\/blog\/suppositoria-jangan-dimakan\/","title":{"rendered":"Suppositoria Jangan Dimakan!"},"content":{"rendered":"<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span>Pernah suatu ketika ada pasien yang<span> <\/span>menerima resep sediaan dengan bentuk suppositoria. Karena si \u201cpenerima\u201d resep tidak memberitahu cara penggunaannya, sang pasien malah memakan dan mengunyah layaknya sebuah coklat namun berasa hambar. Padahal suppositoria memiliki cara penggunaan special. <em>Mengapa spesial?<\/em> Silakan simak penjelasan berikut\u2026<\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span>Suppositoria merupakan s<\/span><span lang=\"IN\">ediaan padat dalam berbagai bobot dan bentuk, yang diberikan melalui rektal, vagina atau <!--more-->uretr<\/span><span>a<\/span><span lang=\"IN\">. Umumnya meleleh, melunak atau melarut pada suhu tubuh. Suppositoria dapat bertindak sebagai pelindung jaringan setempat, pembawa zat terapetik yang bersifat lokal atau sistemik. Bahan dasar suppositoria umumnya adalah adalah lemak coklat, gelatin tergliserinasi, minyak nabati terhidrogenasi, campuran polietilen glikol berbagai bobot molekul dan ester lemak polietilen glikol.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span lang=\"IN\">Beberapa suppositoria untuk rektum di antaranya ada yang berbentuk seperti peluru, torpedo atau jari-jari kecil, tergantung pada bobot jenis bahan obat dan basis yang digunakan, beratnya pun berbeda-beda. USP menetapkan beratnya lebih kurang 2 g untuk orang dewasa bila oleum cacao yang digunakan sebagai basis. Secara umum biasanya suppositoria rektum panjangnya <span style=\"position: relative; top: 2pt;\"><!--[if gte vml 1]><v:shapetype id=\"_x0000_t75\"  coordsize=\"21600,21600\" o:spt=\"75\" o:preferrelative=\"t\" path=\"m@4@5l@4@11@9@11@9@5xe\"  filled=\"f\" stroked=\"f\"> <v:stroke joinstyle=\"miter\" \/> <v:formulas> <v:f eqn=\"if lineDrawn pixelLineWidth 0\" \/> <v:f eqn=\"sum @0 1 0\" \/> <v:f eqn=\"sum 0 0 @1\" \/> <v:f eqn=\"prod @2 1 2\" \/> <v:f eqn=\"prod @3 21600 pixelWidth\" \/> <v:f eqn=\"prod @3 21600 pixelHeight\" \/> <v:f eqn=\"sum @0 0 1\" \/> <v:f eqn=\"prod @6 1 2\" \/> <v:f eqn=\"prod @7 21600 pixelWidth\" \/> <v:f eqn=\"sum @8 21600 0\" \/> <v:f eqn=\"prod @7 21600 pixelHeight\" \/> <v:f eqn=\"sum @10 21600 0\" \/> <\/v:formulas> <v:path o:extrusionok=\"f\" gradientshapeok=\"t\" o:connecttype=\"rect\" \/> <o:lock v:ext=\"edit\" aspectratio=\"t\" \/> <\/v:shapetype><v:shape id=\"_x0000_i1025\" type=\"#_x0000_t75\" style='width:11.25pt;  height:12pt' o:ole=\"\"> <v:imagedata src=\"file:\/\/\/C:DOCUME~171mm0LOCALS~1Tempmsohtmlclip1\u00001clip_image001.wmz\" mce_src=\"file:\/\/\/C:DOCUME~171mm0LOCALS~1Tempmsohtmlclip1\u00001clip_image001.wmz\"   o:title=\"\" \/> <\/v:shape>< ![endif]--><!--[if !vml]--><img decoding=\"async\" src=\"file:\/\/\/C:\/DOCUME~1\/71mm0\/LOCALS~1\/Temp\/msohtmlclip1\/01\/clip_image002.gif\" alt=\"\" width=\"15\" height=\"16\" \/><!--[endif]--><\/span><!--[if gte mso 9]><xml> <o:oleobject Type=\"Embed\" ProgID=\"Equation.3\" ShapeID=\"_x0000_i1025\"   DrawAspect=\"Content\" ObjectID=\"_1308745810\"> <\/o:oleobject> <\/xml>< ![endif]--><span> <\/span>32 mm, berbentuk silinder dan kedua ujungnya tajam.<span> <\/span>Sedangkan suppositoria untuk bayi dan anak-anak, berat dan ukurannya \u00bd dari ukuran dan berat untuk orang dewasa.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span lang=\"IN\">Penggunaan obat dalam suppositoria memiliki keuntungan dibandingkan penggunaan obat melaluia oral, yaitu:<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 35.45pt; text-align: justify; text-indent: -14.15pt; line-height: 150%;\"><!--[if !supportLists]--><span lang=\"IN\"><span>1.<span style=\"font-family: &quot;Times New Roman&quot;; font-style: normal; font-variant: normal; font-weight: normal; font-size: 7pt; line-height: normal; font-size-adjust: none; font-stretch: normal; -x-system-font: none;\"> <\/span><\/span><\/span><!--[endif]--><span lang=\"IN\">menghindari terjadinya iritasi pada lambung.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 35.45pt; text-align: justify; text-indent: -14.15pt; line-height: 150%;\"><!--[if !supportLists]--><span lang=\"IN\"><span>2.<span style=\"font-family: &quot;Times New Roman&quot;; font-style: normal; font-variant: normal; font-weight: normal; font-size: 7pt; line-height: normal; font-size-adjust: none; font-stretch: normal; -x-system-font: none;\"> <\/span><\/span><\/span><!--[endif]--><span lang=\"IN\">menghindari kerusakan obat oleh enzim pencernaan.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 35.45pt; text-align: justify; text-indent: -14.15pt; line-height: 150%;\"><!--[if !supportLists]--><span lang=\"IN\"><span>3.<span style=\"font-family: &quot;Times New Roman&quot;; font-style: normal; font-variant: normal; font-weight: normal; font-size: 7pt; line-height: normal; font-size-adjust: none; font-stretch: normal; -x-system-font: none;\"> <\/span><\/span><\/span><!--[endif]--><span lang=\"IN\">cepat masuk ke saluran darah dan berakibat memberi efek lebih cepat daripada penggunaan obat melalui oral.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 35.45pt; text-align: justify; text-indent: -14.15pt; line-height: 150%;\"><!--[if !supportLists]--><span lang=\"IN\"><span>4.<span style=\"font-family: &quot;Times New Roman&quot;; font-style: normal; font-variant: normal; font-weight: normal; font-size: 7pt; line-height: normal; font-size-adjust: none; font-stretch: normal; -x-system-font: none;\"> <\/span><\/span><\/span><!--[endif]--><span>b<\/span><span lang=\"IN\">agi pasien yang mudah muntah dan tidak sadar.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span lang=\"EN-GB\">Untuk tujuan penting selayaknya basis suppositoria dibagi menurut sifat fisiknya, yaitu basis bersifat minyak atau berlemak; basis yang larut dalam air atau dapat bercampur dengan air; basis-basis lainnya, umumnya merupakan kombinasi dari bahan-bahan lipofilik dan hidrofilik.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span lang=\"EN-GB\">Basis berlemak merupakan basis yang paling banyak dipakai, karena pada dasarnya oleum cacao termasuk kelompok ini, utama dan kelompok ketiga merupakan golongan basis-basis lainnya. Diantara bahan-bahan berminyak atau berlemak lainnya yang biasa digunakan sebagai basis suppositoria : macam-macam asam lemak yang dihidrogenasasi dari minyak nabati seperti minyak palem dan minyak biji kapas. Juga kumpulan basis berlemak yang mengandung gabungan gliserin dengan asam lemak dengan berat molekul tinggi, seperti asam palmitat dan asam stearat, mungkin ditemukan dalam basis suppositoria berlemak.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"text-align: justify; text-indent: 35.45pt; line-height: 150%;\"><span lang=\"EN-GB\">Jadi, Anda sudah tahu seharusnya \u201cdiapakan\u201d jika mendapat resep suppositoria? Ingat, mintalah petunjuk -cara penggunaan dan penyimpanan serta langkah pertama yang dilakukan jika terjadi efek samping- di mana Anda menebus resep. Bertanya adalah HAK Pasien dan Apoteker WAJIB member Informasi. Demi <a title=\"Mengembalikan Jati Diri Bangsa\" href=\"https:\/\/blogkita.info\/sekilas-info\/mengembalikan-jati-diri-bangsa\/\" target=\"_blank\">Mengembalikan Jati Diri Bangsa<\/a> Indonesia. Mulailah saat ini juga \ud83d\ude09<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[11],"tags":[22,23,172],"class_list":["post-45","post","type-post","status-publish","format-standard","hentry","category-obat-dan-penyakit","tag-apotek","tag-apoteker","tag-suppositoria"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.10 - aioseo.com -->\n\t<meta name=\"description\" content=\"Bertanya adalah HAK Pasien dan Apoteker WAJIB member Informasi. Demi Mengembalikan Jati Diri Bangsa Indonesia. 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